Tuesday, April 22, 2008

Little about GENE

What Is a Gene?

Each cell in the human body contains about 25,000 to 35,000 genes, which carry information that determines your traits (say: trates). Traits are characteristics you inherit from your parents; this means your parents pass some of their characteristics on to you through genes. For example, if both of your parents have green eyes, you might inherit the trait of green eyes from them. Or if your mom has freckles, you might inherit that trait and wind up with a freckled face. And genes aren't just in humans — all animals and plants have genes, too.

Genes hang out all lined up on thread-like things called chromosomes (say: kro-moh-somes). Chromosomes come in pairs, and there are hundreds, sometimes thousands, of genes in one chromosome. The chromosomes and genes are made of DNA, which is short for deoxyribonucleic (say: dee-ox-see-ri-bo-nyoo-clay-ik) acid.

Chromosomes are found inside cells, the very small units that make up all living things. A cell is so tiny that you can only see it through the lens of a strong microscope, and there are billions of cells in your body. Most cells have one nucleus (say: noo-clee-us). The nucleus, which is sort of egg-shaped, is like the brain of the cell. It tells every part of the cell what to do. How does the nucleus know so much? It contains our chromosomes and genes. As tiny as it is, the nucleus has more information in it than the biggest dictionary you've ever seen.

In humans, a cell nucleus contains 46 individual chromosomes or 23 pairs of chromosomes (chromosomes come in pairs, remember? 23 X 2 = 46). Half of these chromosomes come from one parent and half come from the other parent. But not every living thing has 46 chromosomes inside of its cells. For instance, a fruit fly cell only has four chromosomes

Each gene has a special job to do. It carries blueprints — the instructions — for making proteins (say: pro-teens) in the cell. Proteins are the building blocks for everything in your body. Bones and teeth, hair and earlobes, muscles and blood, all are made up of proteins (as well as other stuff). Those proteins help our bodies grow, work properly, and stay healthy. Scientists today estimate that each gene in the body may make as many as 10 different proteins. That's over 300,000 proteins!

Like chromosomes, genes come in pairs. Each of your biological parents has two copies of each of their genes, and each parent passes along just one copy to make up the genes you have. Genes that are passed on to you determine many of your traits, such as your hair color and skin color.

What Is Gene Therapy?

Gene therapy uses the technology of genetic engineering to cure or treat a disease caused by a gene that has changed in some way. This is a new kind of medicine, and scientists are still doing experiments to see if it works. One method they are trying is replacing sick genes with healthy ones. Gene therapy trials — where the research is tested on people — and other research may lead to new ways to treat or even prevent many diseases.

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